Oral Health and Nicotine Alternatives: New Evidence from a Systematic Review

A newly published systematic review and network meta-analysis by La Rosa et al. (2025) offers valuable insights into the oral health effects of non-combustible nicotine products (NCNPs). As these products gain popularity as reduced-risk alternatives to smoking, understanding their broader health impact—including on oral health—is critical for clinicians, policymakers, and harm reduction advocates alike. The…

AHA Issues Guidance on Cardiovascular Risks of Smokeless Oral Nicotine Products

On January 7, 2025, the American Heart Association (AHA) released a comprehensive policy statement examining the cardiovascular health implications of smokeless oral nicotine products. Published in Circulation, the statement evaluates emerging products such as tobacco-free nicotine pouches, lozenges, gums, tablets, and gummies, many of which contain synthetic nicotine. This is the AHA’s first detailed update…

Comparative Study Highlights Faster Nicotine Delivery with Bioceramic-Based Pouches

A new preprint study conducted by researchers at Emplicure provides promising evidence that bioceramic calcium sulfate-based nicotine pouches may offer faster and more efficient nicotine delivery than conventional cellulose-based formats. The findings, currently hosted on Research Square, could shape future innovations in nicotine pouch design and regulation. The study, titled Comparative study of calcium sulfate…

Science, Safety & Regulation: The Role of Nicotine Pouches at GFN25

At the 2025 Global Forum on Nicotine in Warsaw, Emplicure Chief Clinical, Regulatory & Quality Officer Dr. Anna Franzén delivered a compelling presentation during the panel “Nicotine Pouches: What’s the Real Story?”.  What Dr. Franzén Shared Dr. Franzén emphasised three critical pillars for nicotine pouches: Established safety of medicinal nicotine — highlighting how regulatory frameworks for nicotine…

What’s Inside a Nicotine Pouch? New Study Sheds Light on Toxicant Profile

As novel nicotine pouches continue to gain traction across global markets, questions around their contents and safety remain top of mind for regulators, public health experts, and adult consumers. A comprehensive study published in the journal Drug and Chemical Toxicology helps answer one of the most pressing questions: What’s actually inside these tobacco-free pouches? 🧪…

Understanding Relative Risk: A Comprehensive Review of Nicotine Products and What It Means for Harm Reduction

A newly updated systematic review and meta-analysis published in F1000Research delivers one of the most comprehensive evaluations to date on the relative risks of nicotine delivery products. The findings are timely—and critical—for public health officials, regulators, and harm reduction advocates working to reshape tobacco policy for the 21st century. 🔍 Study Overview Researchers reviewed 123…

Could Oral Nicotine Pouches Support Harm Reduction in the Middle East?

As smoking rates remain stubbornly high across much of the Middle East and North Africa (MENA), health authorities and policymakers are exploring new ways to remember duce the region’s tobacco-related disease burden. One such possibility—oral nicotine pouches—is starting to enter the conversation. A recent article from Economy Middle East raises the question: Could these smoke-free…