GINNformation: Why Interface Geometry Matters in Nicotine Pouch Design
Executive context Innovation in nicotine pouches has largely focused on formulation variables, nicotine strength, pH, buffering systems, flavours, and moisture content. These factors shape nicotine delivery and user perception and are central to regulatory assessment. However, a growing body of clinical, observational, and design-science evidence indicates that oral tolerability and mucosal outcomes are also strongly…